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The more significantly affected the child is, the higher or lower than normal the blood biomarker is Per the linked study, these proteins are DERM, Calcineurin, suPAR, MAPK14, RELT, EPHB2, C1QR1, PTN, FCN1 These proteins are biomarkers for immune dysregulation, neuroinflammation, and glutamate imbalance
doi: 10.1016/j.msec.2020.111016
Inhibition of the oxidative phosphorylation pathway in neurons can lead to cell death because glycolysis in neurons cannot be activated to the same extent as in astrocytes (Bolanos et al., 1995)
The inflammatory cytokines, taken previously into account, engage a salient role also in patients with NAFLD, as possible liver co-morbidity of opioids dependents, mainly if the attention is focused on the microRNA-26a (miR-26a) that exhibits anti-inflammatory immune effects on immune cells (Yu et al., 2022)
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