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Children and teenagers are most at risk and some people seem to be more susceptible than others

The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria

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Of the 95 downregulated proteins at V2, 48 (51%) were classified as leakage proteins, and 53 were associated with GO-BP terms related to regulation of peptidase activity, inflammatory responses, stress responses, wound healing, immune responses, cytokine production of the Tumor necrosis factor superfamily, and neutrophil chemotaxis

10.1038/s41598-020-70037-7 [DOI] [PMC free article] [PubMed] [Google Scholar] 65.Zaragoza J, Tinsley G, Urbina S, Villa K, Santos E, Juaneza A, et al
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