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This indicated that CBS silencing exerted an inhibitory effect on the xCT system, which significantly reduced intracellular cysteine and GSH levels

Rabbani Z, Jackson I, Zhang X, Xu P, Vujaskovic Z

This was confirmed in other studies in apple (Kadyrzhanova et al., 1999
Crone JS, Lutkenhoff ES, Vespa PM, Monti MM
These approaches aim to enhance treatment efficacy while reducing damage to the normal hematopoietic system, either by selectively inducing LSC clearance or remodeling the bone marrow immune microenvironment
doi: 10.1213/ANE.0000000000005944 [DOI] [PubMed] [Google Scholar] 33.Chen X, Huang T, Cao X, et al