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We reasoned that overt oxidative stress caused by the loss of FH in non-transformed cells could instigate a tumour suppressive mechanism that could explain why Fh1 -deficient animals do not develop carcinomas but only benign cysts 19
Glennon RA, Dukat M, Grella B, Hong SS, Costantino L, Teitler M, et al
& Hirsch, A
10.18632/oncotarget.10130
(values are mean S.D from 6 rats in each group) Figure 7: Activities of superoxide dismutase in Tissues
French physician Michel Pistor developed the technique in 1952, and it has been refined over decades of clinical use in aesthetic medicine worldwide
