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In standard 7H9 media vadK , vadK:vadK His422Ala , vadK:vadK His422Asp and vadK:vadK Arg106Lys Mtb strains grew slower than the parental and complemented strains, but after 21 days incubation, there was no significant differences between the strains (Appendix Fig

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It can lead to neuropathy, megaloblastic anemia, and pernicious anemia, [2] [13] causing symptoms including fatigue, paresthesia, depression, cognitive decline, ataxia, and even irreversible nerve damage
