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Both vitamin C (L-ascorbic acid in particular) and copper peptides are oxidation-sensitive, and very low-pH vitamin C formulas can destabilize the copper-peptide complex

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In some embodiments, formulations or compositions described herein comprise therapeutic agent particles wherein the therapeutic agent is a free base, or a salt, or a prodrug of a therapeutic agent, or any combination thereof

LonnEBoschJYusufSSheridanPPogueJArnoldJMOet al

Copper delivery studied as a carrier of bioavailable copper