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Clinical trial results Phase 2 trial data published in the New England Journal of Medicine showed that participants receiving the highest dose of retatrutide (12mg weekly) achieved 24.2% body weight reduction over 48 weeks

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this replenishes peroxidation-prone lipids for membranes and can either be counterbalanced by antioxidant systems or, when these fail, heighten susceptibility to lipid peroxidation 43