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Aside from sex, baseline demographic and clinical characteristics were generally similar between the two trials, with no statistically significant differences observed (Table 1

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Molecular Mechanisms of Epilepsy An imbalance between excitation and inhibition has long been thought to be one of the main mechanisms that cause spontaneous seizures, based on the classical channelopathy model of epilepsy [27,28]

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High IGF-1 levels could compete for binding to the IGF-1R thus reversing the inhibitory effect of IGF-1R-targeted antibodies [84]

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Consistent with the results acquired from PC cell lines, PDCs with low expression of VRK2 were more sensitive to APR-017 treatment than PDCs with high expression of VRK2 (Fig

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This requires careful management and is beyond the scope of standard starting dose guidance

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[DOI] [PubMed] [Google Scholar] 62.Alves M.B.R., de Andrade A., de Arruda R., Batissaco L., Florez-Rodriguez S.A., Lanoni R., de Oliveira B., Torres M.A., Ravagnani G.M., de Almeida T

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