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Favorable effects of L-carnitine treatment on hypertriglyceridemia in hemodialysis patients: Decisive role of low levels of high-density lipoprotein-cholesterol

Major genes such as cytochrome P450 monooxygenase (CYP1A), Cytochrome b-245 light chain (CYBA), Xanthine dehydrogenase (XDH), and Amine oxidase (flavin-containing) A (MAOA) play an important role in the elevation of ROS or oxidative stress by inducing the expression of NOX3 to form a functional NADPH oxidase, which generates superoxide and other oxidants that are generally repressed by the adaptive response [47]

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While biotransformation processes based on petrochemical achiral precursors have been described for bacterial hosts, fermentative de novo synthesis has not been established although it holds the potential for a sustainable and economical one-pot process using renewable feedstocks