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[DOI] [PubMed] [Google Scholar] 204.Pocernich CB, Butterfield DA

BH4 promotes the synthesis of CoQ10 by converting phenylalanine to tyrosine, thereby serving as a free radical-trapping antioxidant [116]

Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation

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We didn't test whether supplementing with that substance could actually improve patients' symptoms

This would clarify optimal intervention timing, enabling a genuine shift from symptomatic treatment to disease-modifying interventions
