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finally, many antioxidants lack the sufficient reactive capability to neutralize ROS in a timely manner [99] (Figure 7)

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Emdin M, Passino C, Michelassi C, Donato L, Pompella A, Paolicchi A

Methods Cell line and culture conditions The HT29 colorectal cancer cell line was purchased from the American Type Culture Collection (Manassas, VA, USA)

Radiographic films and enhanced chemiluminescence (ECL) reagent (Amersham Pharmacia Biotech, Buckinghamshire, UK) were used for visualizing protein bands

Consequently, it can be hypothesized that there is a reciprocal relationship between NAD + levels and mitochondrial function