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2024 Apr 14];13(1):1-30

Upon stimuli such as starvation or oxidative stress, TFEB is dephosphorylated, subsequently translocates to the nucleus, and promotes the activation of its target genes (Sancak et al., 2010

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However, its crucial to understand that no IV glutathione product is FDA-approved for skin lightening in any major regulatory jurisdiction, and the only placebo-controlled clinical trial showed poor efficacy with serious safety concerns