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Moreover, it has been found that mitochondrial functions and integrity can be affected by many of the risk factors of ASD, including toxins, immune activation, medicines, and metabolic disturbances [17]

Principal component analysis (PCA) was used as an unsupervised approach to explore global metabolic variation between the two groups

Perola M

Beneath the cortex lies the adrenal medulla, which secretes catecholamines involved in the fight-or-flight response

Methods Search strategy Extensive literature search was performed for articles in PubMed and Google Scholar databases until July 13, 2025