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Inhibition of CoQ 10 biosynthesis through the mevalonate pathway or inactivation of CoQ 10 reductases, such as AIFM2/FSP1 or DHODH, induces ferroptosis in settings where GPX4 is not present

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Structure and functions of GSH GSH exists in the thiol-reduced and disulfide-oxidized (GSSG) forms [2]

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Nat Rev Neurosci 20:282297 Racine R, Okujava V, Chipashvili S (1972) Modification of seizure activity by electrical stimulation

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Unlike the classical pathway, the nonclassical pathway relies on the activation of caspase-11 (caspase-4 and caspase-5 in humans)

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& Coe, C

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Snx3 regulates recycling of the transferrin receptor and iron assimilation

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