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35 , 36 However, other mechanism have been proposed, like capability of vitamin B 12 in blocking the activation of COX-2 in experimental colitis
It is also important that you monitor for other symptoms

Before starting B12 injections, its important to consult with a healthcare provider to ensure that B12 deficiency is the underlying cause of your fatigue and to determine the right dosage for your needs

The two mechanisms can be complementary in some plans

Clinical trials tested doses ranging from 250mcg to 1mg daily, with most protocols settling around 300-500mcg for optimal fat metabolism support
