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Diabetes Care 44(5):1203-10 2021 PMC8132317 Wing RR, Look AHEAD Research Group

Methods Male C57BL/6 mice were fed a normal chow diet, HFHC diet, or HFHC diet with enavogliflozin for 12 weeks

Molecular aspects of medicine , 25 (5-6), 455473

Once SCFAs are absorbed into the bloodstream through the walls of the large intestine by a process known as passive diffusion, they are transported to the liver via the portal vein and then distributed to several tissues, where they can interact with specific receptors such as G protein-coupled receptors (GPRs) and influence gene expression, cellular metabolism and immune response (66, 76)

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