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Pham, L.-D
When lymph flow is sluggish, it can lead to swelling, fatigue, and a weakened immune response
10.1007/s11357-019-00051-9 Geroscience 47 GuanY
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The selectivity of IACS-16898 against the bromodomain of CBP and p300 was further evaluated using a DiscoverX BROMOscan assay, which showed high affinity for CBP and p300, demonstrating K d of 0.23 and 0.27 nM, respectively, and a higher than 300-fold (mostly higher than 1000-fold) selectivity against other bromodomains (Fig
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