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10.1016/j.lfs.2024.122951 63 LiS.ZhangB
Sakhaee, Maalouf 2012)
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Ilic S, Brcic I, Mester M, et al
The amino group of the cysteine residue is then acetylated by the intracellular N-acetyltransferase enzymes and thereby forms the mercapturic acid which, depending on its characteristics, is rapidly led to circulation, bile, urine or metabolized until it is eliminated (Figure 3) [22]
In rats and mice, chronic exposure to alcohol causes an increased expression of CYP-2E1 and increases the activity of the enzyme 5- to 7-fold[44, 45]
