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The mechanism whether mediated by weight loss, direct cardiac effects, or reduced inflammation, remains an active area of preclinical and clinical investigation
BO and DS: collection of data, data analysis, and final approval of manuscript
Phospholipids are important structural components of cell membranes, and the sphingolipid, sphingomyelin, is a component of the myelin sheath that enhances nerve transmission (29)
From a vascular point of view, these molecules stimulate ROS production within blood vessels, resulting in endothelial dysfunction, plaque progression, and thrombogenicity [23]

In inflamed and non-inflamed CD patient mucosa, co-culture with bone marrow-derived MSCs increases the apoptosis rate of T cells [113]
J Burn Care Rehabil
