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Examination of the isotopomer distributions for TCA cycle metabolites showed a significant decrease in the percentage of citrate M5 upon glucose deprivation, indicating decreased reductive carboxylation flux from -ketoglutarate to citrate in glucose-deprived cells 28, 29 (Fig

Despite having overall lower efficacy, such dependence was not found for the velocity storage attenuation group (rho = 0.18) (Figure 3B, ), and the group difference was statistically significant ( p = 0.024, Table 1)

To date, no study has used a drug-induced acute renal failure paradigm to investigate the effects of LS on KIM-1 and NGAL levels

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