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Future work should prioritize clinical validation of TMAO-lowering interventions and elucidate tissue-specific mechanisms underlying its dual roles in inflammation resolution and exacerbation

Cole JC, Lin P, Rupnow MF

Dreisbach, AW

Interestingly, the effect of androgens on mitochondrial dynamics may be influenced by the metabolic status and dose of the exogenous androgen, for the failure of testosterone exposure to change these dynamics-related proteins (e.g., DRP1, OPA1, and MFN2) in the skeletal muscle of healthy young women (136)

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