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At the same time, LBP markedly reduced serum and hepatic levels of malondialdehyde (MDA), a lipid peroxidation product, and scavenged hepatic ROS and nitrotyrosine (NTR), established biomarkers of oxidative damage (34, 35, 62, 63)

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For instance, when Prussian Blue (PB) NPs are surface-modified with PEI, the resulting positively charged NPs upregulate POD activity, negatively impacting cell viability as well as liver and kidney functions [159]

Artyomov et al

These findings suggest that peripheral metabolic deficiencies may contribute to sustained neurodegenerative changes in A-T, underscoring the importance of screening, monitoring and addressing these metabolic disruptions in patients