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Adenosine monophosphate-activated protein kinase overactivation leads to accumulation of alpha-synuclein oligomers and decrease of neurites

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Barros M.H., Johnson A., Gin P., Marbois B.N., Clarke C.F., Tzagoloff A

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High organosulfur compounds in garlic essential oil are reported to interact strongly with the amino acids of the angiotensin-converting enzyme (ACE2) protein which prevent COVID-19 and the PDB6LU7 protein (main protease of SARS-CoV-2) (47)

Therefore, -syn aggregation in the skin may play a significant role in PD development
