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Patients with these risk factors should discuss screening and supplementation strategies with their GP, particularly if experiencing symptoms such as fatigue, paraesthesia, glossitis, or cognitive changes suggestive of deficiency

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The insulin-like growth factors (IGFs) in follicular fluid are predominantly bound in the ternary complex

Mecobalamin regulates body functions like cell growth, blood formation, and protein synthesis

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The use of sdAbs such as [ 68 Ga]Ga-NOTA-Nb1053 allows same-day imaging one hour after injection with high target-to-background ratios, avoiding concerns associated with non-specific bone accumulation seen with 89 Zr-labeled mAb immunoPET techniques