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Similarly, mTORC1, primarily via the PI3K/Akt pathway, also enhances the expression and membrane localization of GLUT1 in endothelial cells, promoting glucose uptake (Glaviano et al., 2023)

[DOI] [PubMed] [Google Scholar] Skipsey M., Andrews C.J., Townson J.K., Jepson I., Edwards R

Summary Keywords metabolite, biomarker, major depressive disorder, acetylcarnitine, remission status, drug treatment Citation Lee S, Mun S, Lee Y-R, Choi H, Joo E-J, Kang H-G and Lee J (2022) Discovery and validation of acetyl-L-carnitine in serum for diagnosis of major depressive disorder and remission status through metabolomic approach

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doi: 10.1038/s41580020-00324 8 Zeng FTNijiatiSTangLYeJZhouZChenX

A multicenter Phase III clinical trial confirmed that elagolix significantly reduces menstrual blood loss associated with uterine fibroids, with efficacy unaffected by age, body mass index, ethnicity, baseline bleeding volume, or fibroid location [160]