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This is based on the current body of research and our observations of trends in the scientific community

Gastrointestinal disturbances : Instances of nausea, bloating, or abdominal discomfort have been noted

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Specifically, SM/J mice, known for their poor regenerative capacities, displayed early spontaneous onset IDD that was marked by early onset cellular and matrix changes that were consistent with human IDD, such as loss of NP/AF boundary, formation of small clusters in the NP, and chondrocyte-like cells surrounded by proteoglycan-rich matrix (Zhang et al., 2018)

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