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Specific to CoV, in vitro studies demonstrate that RV inhibits MERS-CoV infection by decreasing nucleocapsid protein expression resulting in reduced viral production and increased cell survival 33

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Constitutive skin pigmentation is the result of genetically determined epidermal melanin levels, although there are regulatory factors that affect total epidermal melanin levels

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Curcumin can restore leptin-induced tight junction dysfunction in intestinal Caco-2 BBe cells by increasing the expression of tight junction proteins, repairing inflammation-induced impairment of the blood-milk barrier function, enhancing alveolar epithelial integrity under hypoxic conditions, increasing the diabetes-induced blood-retinal barrier capacity, and improving the barrier function of the blood-brain barrier under ischemic conditions