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& Sourjik, V

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7a, b) and that the full three-dimensional structures of other BH3-only proteins were not known with the exception of BID, which, unlike BNIP3, requires cleavage for activation 1 , we decided to use BAX as a template (PDB codes 2K7W, model 1 28 and 2KA1 26 )

It is noticeable that there exist medicines increasing SIRT1 activity, for example, resveratrol [152] or salvianolic acid B [154], which can promote correction of redox imbalance through an increase in activity of Nrf2 [154] and, likely, FoxO, as well as through a decrease in the activity of NF- B

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