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That substance is glutathione

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Additionally, iron overload leads to the release of high mobility group protein 1 (HMGB1) in the damage-associated molecular patterns (DAMPs) released from cells

Nonlinear pharmacokinetic properties of mildronate capsules: a randomized, open-label, single- and multiple-dose study in healthy volunteers

This imbalance leads to a reduced presence of bacteria capable of synthesizing SCFAs (60, 61)