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The relevance to human subcutaneous dosing is uncertain

TFEB (facteur de transcription EB), dans des conditions de stress lysosomal induit par des lipides athrognes tels que les LDL oxydes, dclenche la biogense lysosomale, notamment une expression accrue du gne LIPA (Induction of Lysosomal Biogenesis in Atherosclerotic Macrophages Can Rescue Lipid-Induced Lysosomal Dysfunction and Downstream Sequelae 2014)

We find that light exposure causes oxidative stress and induces canonical stress responses

SHARMAN MARTYN R

Xanthine oxidase inhibition by febuxostat attenuates experimental atherosclerosis in mice

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