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The two isoforms of CRP are involved in the process of atherosclerosis: the pentameric CRP (pCRP) isoform attaches to the phosphatidylcholine present on the surface of apoptotic cells and starts inflammation [35], while monomeric (mCRP) modulates platelet function and promotes thrombosis inside the lumen of the vessels by stimulating platelet aggregation (Figure 1) [36,37]

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A Q ExactiveTM HF mass spectrometer was operated in positive or negative polarity mode with a spray voltage of 3.2 kV, capillary temperature of 320C, sheath gas flow rate of 40 arb, and aux gas flow rate of 10 arb

Thereafter, blood samples were centrifuged at 2000 g for 15 min at 4 C

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A follow-up study showed that NAC administered during two 3-day inpatient hospitalizations separated by 4 days reduced the desire for cocaine use induced by drug-related cues, as well as decreased interest and time for a view cue [77]