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Clinical trials in head and neck cancer report improved antioxidant enzyme activity, but robust phase III data are lacking

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This combination works through complementary pathways that enhance nitric oxide (NO) production, bioavailability, and stability -- delivering benefits that exceed simple addition of their individual effects

Mol Med Rep 2017

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Then, measurements (hallmarks of skin and nail aging, dermal density, skin moisture, elasticity, wrinkles, and nail color) were conducted at baseline, 4 weeks, and then 12 weeks