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This structural characteristic explains the compounds extraordinary stability: testing demonstrates it remains intact in human gastric juice for more than 24 hours , a property virtually unheard of among peptide therapeutics

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Dulaglutide Dulaglutide is another GLP- 1 synthetic analog which consists of two DPP- 4 resistant GLP- 1 molecules that are covalently linked to a modified IgG4 Fc fragment that acts as carrier, limiting the renal clearance of the molecule [93]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Yan Y., Liang H., Yang S., Wang J., Xie L., Qin X., Li S