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Serum antipyrine, which is metabolized by at least 10 CYP isoforms, is used to measure in vivo hepatic CYP activity

Brain iron accumulation Cerebral iron accumulation, a prevalent comorbidity in a multitude of cognitive and motor function disorders such as AD, PD, multiple system atrophy, and multiple sclerosis, is often evidenced by heightened iron deposition in the brain [469, 503, 798803]

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