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[DOI] [PubMed] [Google Scholar] 72.Roland A., Patterson R.A., Leake D.S

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Pre-existing inborn errors of sulfur-amino-acid metabolism (e.g., homocystinuria) represent an absolute contraindication because parenteral methionine can exacerbate elevated homocysteine concentrations and associated thrombotic risk

Unlike NSAIDs, acetaminophen does not cause stomach irritation or increased bleeding risk, making it a preferred choice for individuals sensitive to gastrointestinal side effects