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[2] [11] As of 2026, retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA), and it remains an experimental compound available only within authorised clinical trial settings

Arteriovenous haemangiomas, presenting as bluish erythematous papules on the neck and chest, are associated with elevated estrogen levels in cirrhosis (91, 92)

This damage can manifest as anything from tingling and numbness in the extremities to more severe issues

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In certain cases, breakouts or dryness may also occur as the skin adjusts