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On the other hand, the pathophysiology of type 1 diabetes mellitus (T1DM), which accounts for 10% of all cases of diabetes, classically involves the autoimmune destruction of -cells in the pancreas by invading CD4+ and CD8+ T-cells and macrophages

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The paper summarized results from rat model experiments demonstrating interactions of the peptide with the dopaminergic (including effects on D2 receptors), serotonergic, and GABAergic systems