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These results indicate that BB is a major gut microbial metabolite formed from oral l-carnitine in humans (for both omnivores and vegans/vegetarians)

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Activation of mTORC1 and subsequent phosphorylation of downstream targets stimulates protein synthesis, leading to increases in skeletal muscle fiber size and mass (Bodine et al., 2001b)

In terms of the blinding of participants and personnel, one trial (Kortam, Abdelrahman & Fateen, 2020) had unclear risk of bias, and one trial (Talari et al., 2019) had high risk of bias, as the researchers and participants were not blinded in their trial

Platelet activation, aggregation, and subsequent intra-arterial thrombosis are important steps in atherosclerotic thrombosis, and enhanced platelet reactivity is associated with the degree of terminal organ injury and poor prognosis ( 2+ release from intracellular stores ( in vivo can potentially lead to thrombosis, and within the physiological range of TMAO concentration observed in human and animal models, the effect of TMAO on platelet function is dose-dependent