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Cholesterol is necessary for creating new cells, producing hormones, making vitamin D, and creating bile (a fluid that aids in digestion)

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The proposed DDMSNs-CPT-CuS exhibited well performances, such as easy preparation, low cytotoxicity and high photothermal conversion efficiency

Ferroptosis was observed in PAECs from MCT-induced PH rats in vitro and in vivo and was characterized by a decline in cell viability accompanied by increases in the LIP and lipid peroxidation, the downregulation of GPX4 and FTH1 expression and the upregulation of NOX4 expression