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138 Simultaneously, SIRT3 can not only induce the expression of antioxidant enzymes by activating the FOXO3a, but also enhance the activation of SOD2 and catalase via NAD + -dependent deacetylation

In the absence of an initial upregulation of NAD + -GDH gene transcription under conditions of ammonium starvation, the observed increase in NAD + -GDH aminating activity might possibly be attributed to other control mechanisms, such as the GarA-pknG regulatory system

It works by interacting with DNA expression and the pineal gland to help regulate natural cellular processes

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of reactive oxygen species (ROS) via Fenton reaction chem