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According to current FDA-approved protocols for the treatment of acute acetaminophen ingestion, oral acetylcysteine is given as a loading dose of 140 mg per kilogram of body weight, with maintenance doses of 70 mg per kilogram that are repeated every 4 hours for a total of 17 doses

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[DOI] [PubMed] [Google Scholar] 38.Yi P., Melnyk S., Pogribna M., Pogribny I.P., Hine R.J., James S.J

Buckwalter, M

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