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[DOI] [PMC free article] [PubMed] [Google Scholar] 158.Schaur R.J., Siems W., Bresgen N., Eckl P.M

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plantarum SAL ameliorates these aging-related phenotypes by modulating microbial composition, notably enriching the abundance of beneficial bacteria and reducing the pathogenic bacteria

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The elevated levels of microglia activating factors, including M-CSF, MCP-1/CCL2, TNF-, IL6, INF-, and TGF-, were identified in the CNS of ALS patients or ALS mouse and cellular models (Yoshihara et al., 2002

Interestingly, the effect of CRY mutation on the expression of NF-B targets genes and NF-B biding to their promoters was reversed by BMAL1 down-regulation