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The liberation of Nrf2 from Keap1 allows Nrf2 accumulation and translocation to the nucleus (Cuadrado et al., 2019

We believe that this perspective will comprise a cumulative source of melanogenesis inhibitors for researchers and further understanding of anti-melanogenesis chemotherapy
Peng H, Dou H, He S, Xie YA, Zheng J

Risk factors, pathogenesis, and strategies for hepatocellular carcinoma prevention: emphasis on secondary prevention and its translational challenges
One way UV light speeds up aging is by enhancing free radical production
