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[DOI] [PMC free article] [PubMed] [Google Scholar] Sun W-M, Huang Z-Z, et al
Common molecular mechanisms of SLC6A1 variant-mediated neurodevelopmental disorders in astrocytes and neurons

Understanding these distinctions is crucial for healthcare providers and patients when considering the most suitable treatment option: Mechanism of Action: Tesofensine, a triple monoamine reuptake inhibitor, primarily affects neurotransmitter levels in the brain, impacting appetite and potentially energy expenditure

NRF2 stimulates the production of heme oxygenase-1 (HO-1) and the accumulation of Fe 2+ in LIP as well as the release of iron from hemoglobin, hence inducing ferroptosis

some individuals report pronounced improvements in sleep and mood, while others notice minimal effects

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