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& Ronco, C

Redox Biol 41:101950

After a 48 h exposure to 100 M H 2 O 2 in serum-free medium, TM3 Leydig cells showed an increased senescence-associated -galactosidase (SA--gal) activity (Figure 3A)

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Despite the substantial conformational dynamics when bound to AMY 3 R, Cagri maintains the bypass conformation across the motions, likely arising from the consistent TMD and linker interactions between RAMP3 and CTR that enable robust engagement of residues within the Cagri bypass motif

GSH transport into mitochondria appears to be mediated in part by the dicarboxylate carrier (DIC, Slc25a10) and the oxoglutarate carrier (OGC, Slc25a11) (Lash, 2006), whereas transport into the nucleus probably occurs by passive diffusion through the nuclear pores