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TNF- and IL-1 are key inflammatory mediators of IDD, positively correlating with the severity and promoting ECMs catabolism by up-regulating proteolytic enzymes, whilst inhibiting the expression and synthesis of proteoglycan (Le Maitre et al., 2005

10.1128/MCB.01874-07 229

A trigger point injection typically includes: Saline Lidocaine (a local anesthetic) Toradol (an anti-inflammatory medication) Steroid (for more persistent inflammation) Or Botox for more long-term muscle relaxation Each solution is chosen based on the patients unique symptoms, lifestyle, and medical history

J Cell Mol Med 13(2):309319 Alvero AB et al (2009) Stem-like ovarian cancer cells can serve as tumor vascular progenitors

[DOI] [PMC free article] [PubMed] [Google Scholar] 233.Ogunsola O.A., Kraeling M.E., Zhong S., Pochan D.J., Bronaugh R.L., Raghavan S.R