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Description
2021: A systematic review of three RCTs compared 234 participants taking 2 g/day oral propionyl-L-carnitine for 46 months with 222 patients on placebo

Comparative Analysis: For male fertility, L-carnitine appears more beneficial, whereas ALC might offer additional support for female fertility issues

A trial in 150 participants with either ovarian cancer or castration-resistant prostate cancer found no evidence that ALCAR (1g every 3 days) given with the anticancer drug sagopilone (for up to six cycles of treatment) reduced the overall risk of peripheral neuropathy compared to a placebo (90)

Treatment with acetylcarnitine alone or as a part of a combined dietary intervention has resulted in reduced levels of fatigue, decreased depression, improved cognitive status, and/or improved physical function in these disorders

Molecular regulation of fatty acid oxidation in skeletal muscle during aerobic exercise

doi: 10.4161/psb.6.10.16876
