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Figure 3 Regulatory T cells (Tregs) have been shown in multiple models to rely on a high antioxidant capacity, characterized by low ROS levels and elevated glutathione (GSH), as well as active GCN2 signaling (158, 159)
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N Engl J Med 366 (18): 1663-73, 2012
Factors such as sleep, nutrition, stress levels, and metabolic health all influence how the body responds over time
Unfortunately, cohort studies conducted in 2012 did not confirm the role of polymorphisms in genes GSTM1 , GSTT1 , and GSTP1 in the development of AMD [108]
This increase temporally correlates with dietary westernization, including greater consumption of red and processed meats
