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10.1093/toxsci/kfm148 112 MeolaJ.RosaE.SilvaJ

Recent reviews have highlighted this issue [108, 109]

Ursolic acid ameliorates CCl4-induced liver fibrosis through the NOXs/ROS pathway

Despite advances in surgical techniques, radiation therapy, and chemotherapy, the overall survival rates for HNSCC have only modestly improved over the past few decades

Among the botanical drugs and polyherbal formulations reviewed, only Curcuma longa (Sukonthanonta, 2015) , Camellia sinensis (Roshdy et al., 2013), and GZFLW ( Curcuma longa were limited without the presence of a negative control group, while a systematic review of randomized clinical trials conducted on GZFLW revealed that the trials have a high risk of bias, with no description of the allocation concealment of the participants

Combining genetic context with liver-function biomarkers and medication history enables more personalized decisions about supplementation safety, timing, and expected outcomes