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doi:10.1111/jfbc.13989 49

However, if you have a B-12 deficiency, correcting low folate levels may simply mask the deficiency and fail to fix the underlying problem

Methods: RECOVER-S is a multi-center, stroke rehabilitation cohort investigating clinical trajectories and rehabilitation pathways of patients in Berlin, Germany (trial identifier: DRKS00030023)
Swindell, W

Several factors can impair B12 absorption: Reduced stomach acid production (achlorhydria or hypochlorhydria), common in older adults and those taking proton pump inhibitors or H2-receptor antagonists long-term, impairs the release of B12 from food proteins Pernicious anaemia , an autoimmune condition destroying parietal cells and reducing intrinsic factor production, completely blocks the primary absorption pathway Gastrointestinal disorders including Crohn's disease, coeliac disease, or surgical removal of stomach or ileum sections directly damage absorption sites Metformin , commonly prescribed for type 2 diabetes, may reduce B12 absorption through unclear mechanisms

Another weight loss peptide is semaglutide